If you're a nurse in Mississippi aiming to enhance your resume, step into leadership positions, or become a nurse practitioner, enrolling in a graduate-level nursing program is a key step forward. Many nurses in Mississippi opt for Master of Nursing Science (MSN) programs due to their shorter duration and comparatively affordable tuition, making them an excellent choice for balancing career advancement with a busy work schedule.

In the sections below, we’ll discuss how to choose the right MSN program and highlight some of the most affordable and accelerated options available in the Southern State of Mississippi, whether you're based in Jackson, Gulfport, Hattiesburg, or one of the state’s charming rural communities.

2027 Best Online MSN Programs in Mississippi

Registerednursing.org has ranked the best online MSN programs in Mississippi to help nurses advance their careers without putting life on hold. Online education opens doors for working professionals, offering flexibility to balance job, family, and school. These programs use distance learning to deliver coursework, with many relying on virtual platforms. Hybrid and partially online programs count as online, so nurses can find options that fit their needs. Whether aiming for leadership, education, or advanced clinical roles, an online MSN makes it possible. The rankings highlight quality and accessibility, so choose a program that aligns with goals. For full details on how these rankings were determined, visit https://www.registerednursing.org/rankings-methodology/.
#1

Delta State University

Cleveland, MS - Public 4-Year - deltastate.edu

BSN to MSN - Master of Science in Nursing (Nurse Educator)

Online & Campus Based - Visit Website

Delta State University offers a Master of Science in Nursing with a Nurse Educator concentration in a hybrid format, combining online coursework with on-campus elements. Admission requires a 3.0 GPA, GRE scores from the past five years, and at least one year of clinical nursing experience. Applicants need a current RN license, three letters of recommendation, and must complete a pathophysiology prerequisite. The program includes three specialty tracks and an interview with graduate faculty. This flexible structure accommodates working nurses seeking to transition into academic or clinical education roles.

  • 3 concentration options
  • Entrance exam required
  • Exams: GRE
  • 3.0 GPA minimum
  • 3 letters of recommendation (minimum)
  • Work experience required
  • Prerequisite courses required
  • Requires GRE scores within 5 years
  • Clinical experience required for all tracks
  • Pathophysiology prerequisite for Nurse Educator

BSN to MSN - Master of Science in Nursing (Family Nurse Practitioner)

Online & Campus Based - Visit Website

Designed for aspiring advanced practice nurses, Delta State University's online/hybrid MSN with a Family Nurse Practitioner concentration offers both full-time (two-year) and part-time options. The CCNE-accredited program requires a BSN with a 3.0 GPA, GRE scores, and one year of recent RN experience. Coursework is delivered online with strategically scheduled campus seminars, and clinical placements can be arranged near students' communities with faculty approval. Applications are due February 1, and the non-traditional class schedule supports working professionals. Multiple NP tracks and post-master's certificates are also available.

  • Family Nurse Practitioner concentration
  • Hybrid online and campus format
  • Full-time study in 2 years
  • Part-time study available
  • CCNE accredited program
  • 3.0 minimum GPA required
  • GRE entrance exam required
  • One year RN experience required
  • February 1st application deadline
  • Clinical placements near home

BSN to MSN - Nurse Administrator

Online & Campus Based - Visit Website

Delta State University's MSN in Nurse Administration, offered through the Robert E. Smith School of Nursing, provides a hybrid learning environment with online courses and occasional campus seminars. This CCNE-accredited program requires a BSN with a 3.0 GPA, GRE scores, one year of RN experience, and current Mississippi nursing licensure. Students can choose full-time (two-year) or part-time study, with clinicals arranged close to home. The application deadline is February 1, though applications are accepted year-round; an interview is required. Post-master's certificate options and multiple role concentrations are also available for career advancement.

  • Master of Science in Nursing degree
  • Nurse Administrator concentration offered
  • Hybrid online and campus format
  • Online courses with campus seminars
  • Full-time study in 2 years
  • Part-time study available
  • Non-traditional class schedule
  • Clinicals near student's home
  • BSN with 3.0 GPA required
  • GRE scores required
Show 2 More Programs ˅
#2

William Carey University

Hattiesburg, MS - Private 4-year - wmcarey.edu

BSN to MSN - Master of Science degree in Nursing Education (Nurse Educator)

Online Learning - Visit Website

William Carey University offers an online Master of Science in Nursing Education with a Nurse Educator concentration, designed for registered nurses seeking faculty or staff development roles. The 36-credit curriculum can be completed in one year of full-time or two years of part-time study, with 100% asynchronous online coursework. Admission requires a baccalaureate degree from an accredited nursing program, an active RN license, a minimum 3.0 GPA, and two nursing recommendations; no entrance exam is specified in the published requirements. The program includes 180 clinical hours and a local preceptorship, emphasizing leadership, research, and interprofessional collaboration within a Christian framework. Accredited by the Commission on Collegiate Nursing Education, this MSN prepares graduates for nurse educator certification and careers in academic or clinical education settings.

  • Commission on Collegiate Nursing Education accredited
  • 1-Year program
  • 36 total credit hours
  • Full-time and part-time options
  • Asynchronous online classes
  • 3.0 GPA minimum
  • 2 letters of recommendation (minimum)
  • 180 clinical hours
  • Work experience required
  • Prerequisite courses required
#3

Mississippi College

Clinton, MS - Private 4-year - mc.edu

BSN to MSN - MSN Clinical Nurse Leader

Online Learning - Visit Website

Mississippi Christian University's online MSN in Clinical Nurse Leader prepares RNs for advanced leadership roles in healthcare. The program features fully online, accelerated courses in seven- or eight-week formats, allowing flexibility for working professionals. With 35-36 credit hours, it can be completed in 18-24 months, with total tuition ranging from $21,000 to $21,600. Admission requires a BSN from an accredited institution, an active RN license, a 2.5 GPA, and a satisfactory background check. Students engage in clinical practicums and a capstone project, focusing on evidence-based practice, care coordination, quality improvement, and healthcare systems. The program holds CCNE accreditation and integrates Christian values, preparing graduates for CNL certification and diverse clinical settings.

  • Fully online format.
  • Accelerated seven or eight-week courses.
  • Total tuition $21,000-21,600.
  • Duration 18-24 months.
  • 35-36 credit hours.
  • Clinical Nurse Leader track available.
  • Clinical practicum over full semester.
  • Select own preceptor and site.
  • Capstone project required.
  • Admission requires BSN degree.
#4

University of Southern Mississippi

Hattiesburg, MS - Public 4-Year - usm.edu

BSN to MSN - Nursing (Psychiatric-Mental Health Nurse Practitioner), M.S.N.

Online & Campus Based - Visit Website

The University of Southern Mississippi offers an online MSN with a Psychiatric-Mental Health Nurse Practitioner emphasis, delivered in a hybrid format that combines web-based coursework with in-person clinical practica. Designed for registered nurses holding a BSN, this program requires applicants to submit GRE scores, maintain a 3.0 GPA, possess a current RN license, and have at least one year of clinical experience. The 34-48 credit hour curriculum includes psychobiological theories, psychopharmacology, advanced health assessment, and family psychiatric care, culminating in eligibility for national certification. Students must sustain a 3.0 GPA, pass a comprehensive exam, and complete background checks, liability insurance, CPR certification, and HIPAA/CITI training. Clinical practicum courses and a transition-to-practice seminar prepare graduates for advanced psychiatric nursing roles.

  • Hybrid program format.
  • 34-48 credit hours.
  • BSN required for admission.
  • 3.0 GPA minimum requirement.
  • GRE scores required.
  • Current RN license needed.
  • One year clinical experience.
  • CPR certification required.
  • Health exam proof needed.
  • Three reference letters.
*Data reference: IPEDS 2025, U.S. Department of Education, NCES.

RN to MSN Programs in Mississippi

A traditional MSN program usually takes three to four years to complete, but many nurses in Mississippi find it challenging to balance full-time education with their demanding schedules. For those who have already earned an associate degree in nursing and hold an RN license, an RN to MSN program offers a more convenient and cost-effective alternative. These bridge programs enable nurses to gain the qualifications needed for advanced nursing roles in significantly less time, often cutting the duration in half.

Typical admissions requirements for RN to MSN programs include:

  • Mississippi RN license
  • ADN or nursing diploma
  • GPA transcripts (usually 3.0 or higher)
  • Professional nursing experience (often 1–2 years of clinical practice)
  • Letters of recommendation, a personal statement, and/or a resume

If you’re interested in applying to RN to MSN programs in Mississippi, check out University of Mississippi (Ole Miss) which offers the only one in the state.

Jackson, MS

School of Nursing
2500 North State Street
Jackson, MS 39216
(601) 984-6220

Are we missing your school's program or need to update information listed? Please contact us so we can make the necessary changes.

Fast & Affordable MSN Programs in Mississippi

You don't have to give up your hard-earned income or precious time to pursue a graduate-level education. Mississippi offers a variety of affordable, fast-paced, and flexible MSN programs designed for working professionals. Here are some tips for finding the best MSN programs in Mississippi, along with examples to get you started.

What Are the Fastest Online MSN Programs?

MSN programs are inherently a quick choice for advancing your nursing career, but in Mississippi, some options are even faster than others. One way to streamline your education is by establishing residency in the state before applying, which can help you qualify for in-state tuition rates. Additionally, many programs offer online options, allowing you to complete coursework at your own pace. Here are a few examples of the fastest MSN programs in Mississippi.

SchoolEstimated LengthOnline Option?
University of Southern Mississippi (USM)5 SemestersYes
Mississippi College (MC)18 – 24 MonthsYes
Mississippi University for Women (MUW)12 MonthsNo

What Are the Most Affordable Online MSN Programs?

While Mississippi is known for its relatively low cost of living, that doesn't always guarantee that local schools are budget-friendly. To locate the most affordable MSN programs in Mississippi, it's essential to do your research. Below are a few examples of schools in Mississippi that offer MSN programs with reasonable tuition rates.

SchoolEstimated CostCredits
Mississippi University for Women (MUW)$9,000 – $14,00039
University of Mississippi (Ole Miss)$15,000 – $20,00042
Delta State University (DSU)$21,000 – $23,00045 – 48

See Related Articles

Accelerated MSN & Master's Entry to Nursing Practice (MENP) 

Accelerated MSN & Master's Entry to Nursing Practice (MENP) programs in Mississippi provide a fast-track option for individuals holding a bachelor's degree in a non-nursing field who wish to transition into the nursing profession. These direct-entry programs blend foundational nursing coursework with advanced practice studies, allowing students to earn both a BSN and MSN through a streamlined, intensive curriculum. Graduates of MENP programs are eligible for RN licensure and advanced practice positions, making these programs an excellent choice for career changers seeking a quicker route into nursing. Here are the full list of requirements:

  • Bachelor's degree
  • Minimum GPA (often 3.0+)
  • GRE or TEAS scores (if required)
  • Transcripts, recommendations, personal statement, resume
  • Healthcare experience (preferred or required)
  • Admissions interview

Once you’re ready to start applying, consider looking at Mississippi State University (MSU), which offers the only MENP program in the state.

Schools Offering Popular MSN Specialties

One of the great advantages of MSN programs in Mississippi is the opportunity to specialize in a specific area of nursing. These specializations can focus on clinical practice, such as family or psychiatric-mental health nursing, or non-clinical areas such as nursing education or administration. Below are a few examples of specialized MSN programs available in Mississippi.

SchoolSpecialtyCredits
University of Southern University (USM)Family Nurse Practitioner34 – 43
Delta State University (DSU)Family Nurse Practitioner65
University of Mississippi (Ole Miss)Adult-Gerontology Acute Care Nurse Practitioner39

What is MSN Accreditation?

As you explore MSN programs in Mississippi, it's crucial to verify that each one is accredited. MSN accreditation ensures that a Master of Science in Nursing program meets the rigorous standards set by organizations such as the Commission on Collegiate Nursing Education (CCNE) and the Accreditation Commission for Education in Nursing (ACEN). Accredited programs are designed to prepare students for advanced nursing roles, licensure, and certification, making them essential for career advancement. Additionally, accredited programs are widely recognized by employers and qualify for financial aid opportunities.

2026 List of MSN Programs in Mississippi

Are you looking for other options than the ones listed above? Take a look at the full list of MSN programs in Mississippi listed below:

MSN Programs By City:

Browse Our List of Programs

We've put together a handy list of programs to make your search easier. The table below shows each school's city and state, program highlights, and a link to their official program page. Take a look and compare your options. When something sparks your interest, follow the link to get the full details. This is a simple way to explore what's out there and find the program that fits your needs.
Jump to City:

Cleveland, MS

Delta State University

  • BSN to MSN - Master of Science in Nursing

    Concentration: Family Nurse Practitioner - Online & Campus Based - Website

    • Family Nurse Practitioner concentration
    • Hybrid online and campus format
    • Full-time study in 2 years
    • Part-time study available
    • CCNE accredited program
    • 3.0 minimum GPA required
    • GRE entrance exam required
    • One year RN experience required
  • BSN to MSN - Master of Science in Nursing

    Concentration: Nurse Educator - Online & Campus Based - Website

    • 3 concentration options
    • Entrance exam required
    • Exams: GRE
    • 3.0 GPA minimum
    • 3 letters of recommendation (minimum)
    • Work experience required
    • Prerequisite courses required
    • Requires GRE scores within 5 years
  • BSN to MSN - Nurse Administrator

    Online & Campus Based - Website

    • Master of Science in Nursing degree
    • Nurse Administrator concentration offered
    • Hybrid online and campus format
    • Online courses with campus seminars
    • Full-time study in 2 years
    • Part-time study available
    • Non-traditional class schedule
    • Clinicals near student's home

Clinton, MS

Mississippi College

  • BSN to MSN - MSN Clinical Nurse Leader

    Online Learning - Website

    • Fully online format.
    • Accelerated seven or eight-week courses.
    • Total tuition $21,000-21,600.
    • Duration 18-24 months.
    • 35-36 credit hours.
    • Clinical Nurse Leader track available.
    • Clinical practicum over full semester.
    • Select own preceptor and site.

Columbus, MS

Mississippi University for Women

  • BSN to MSN - Master of Science in Nursing

    Concentration: Family Nurse Practitioner - Campus Based - Website

    • 39 semester hours required
    • 12-month program length
    • Family Nurse Practitioner track
    • BSN and RN experience required
    • Primary care focus
    • Advanced nursing practice
    • Evidence-based practice
    • Prepares for doctoral education

Hattiesburg, MS

University of Southern Mississippi

  • BSN to MSN - Nursing (Psychiatric-Mental Health Nurse Practitioner), M.S.N.

    Online & Campus Based - Website

    • Hybrid program format.
    • 34-48 credit hours.
    • BSN required for admission.
    • 3.0 GPA minimum requirement.
    • GRE scores required.
    • Current RN license needed.
    • One year clinical experience.
    • CPR certification required.
  • BSN to MSN - Nursing Executive

    Campus Based - Website

    • MSN with Nursing Executive emphasis.
    • 34-43 credit hours required.
    • Campus-based program.
    • 3.0 GPA for admission.
    • GRE scores required.
    • RN license needed.
    • Background check required.
    • Core courses include policy.

William Carey University

  • BSN to MSN - Master of Science degree in Nursing Education

    Concentration: Nurse Educator - Online Learning - Website

    • Commission on Collegiate Nursing Education accredited
    • 1-Year program
    • 36 total credit hours
    • Full-time and part-time options
    • Asynchronous online classes
    • 3.0 GPA minimum
    • 2 letters of recommendation (minimum)
    • 180 clinical hours
*Data reference: IPEDS 2025, U.S. Department of Education, NCES.