For Advanced Practice Registered Nurses (APRNs) who want to pursue a second specialty, South Carolina's post-graduate certificates in nursing are the perfect solution. These certificates help working nurses advance their careers by expanding the number of roles they are qualified to fill. For example, a nurse with an APRN designation of Family Nurse Practitioner might pursue a post-graduate certificate to gain the designation of Adult-Gerontology Nurse Practitioner.

2027 Best Online Nursing Post-Master's Graduate Certificate Schools in South Carolina

Registerednursing.org ranks the best online nursing post-master's graduate certificate schools in South Carolina. These programs let working nurses advance their skills without putting their careers on hold. Online learning offers flexibility that traditional classrooms cannot match, making it easier to balance work, family, and education. We consider hybrid and partially online programs as online, so more schools qualify. Whether you prefer distance learning or a more structured virtual format, the right fit exists. Our rankings highlight schools that combine quality education with practical convenience. To see how we evaluate each program, visit https://www.registerednursing.org/rankings-methodology/
#1

University of South Carolina

Columbia, SC - Public 4-Year - sc.edu

Graduate Certificate - Nursing Education

Online Learning - Visit Website

The University of South Carolina's online Nursing Education Post-Master's Certificate equips MSN-prepared nurses with the pedagogical skills needed for academic and clinical instruction. The National League for Nursing-accredited program covers curriculum development, instructional strategies, assessment methods, and evidence-based teaching practices. Students learn to design learning experiences and evaluate outcomes, fostering educational leadership. Graduates may pursue roles as nursing faculty, clinical educators, or staff development specialists and are eligible for the CNE certification exam. Offered in full- and part-time formats, the certificate starts in fall and requires a 3.0 GPA and three letters of recommendation. Applications are due June 30, 2025. State authorization restrictions may apply.

  • National League of Nursing accredited
  • Apply by 2025-06-30
  • Full-time and part-time options
  • Starts fall
  • 3.0 GPA minimum
  • 3 letters of recommendation (minimum)
  • Prepares for CNE
  • Prepares for CNE certification exam
  • Online program format
  • For nurses with MSN degrees

Graduate Certificate - Family Nurse Practitioner, Certificate

Online Learning - Visit Website

University of South Carolina's online Family Nurse Practitioner Certificate prepares post-master's nurses for national certification and advanced primary care practice across the lifespan. The program requires 18-32 credit hours, including 21 concentration credits covering pediatric and women's health, chronic condition management, and legal/ethical frameworks. Clinical practicum and some on-campus immersion are part of the curriculum, with two entry points and GAP analysis for APRNs. Admission requires an MSN with a minimum 3.00 GPA. Graduates are equipped for direct patient management in varied primary care settings, with role transition preparation integrated throughout.

  • Post-master's certificate program.
  • Requires master's degree in nursing.
  • Prepares for national certification.
  • 18-32 credit hours required.
  • Minimum 3.00 GPA needed.
  • Online program format.
  • Two entry points available.
  • Includes practicum courses.
  • Some on-campus immersion.
  • Advanced practice preparation.

Graduate Certificate - Psychiatric Mental Health Nurse Practitioner, Certificate

Online Learning - Visit Website

The University of South Carolina's online Psychiatric Mental Health Nurse Practitioner Certificate readies post-master's nurses for national certification in holistic, lifespan mental health care. The 18-32 credit curriculum integrates neuroscientific principles, psychopharmacology, psychiatric evaluation, and trauma-informed care. Students complete advanced practice core and PMHNP concentration courses, along with practicum hours and some on-campus immersion. Designed for APRNs and non-APRNs, the program offers two entry points; GAP analysis determines individualized plans. Admission requires an MSN with a 3.00 GPA. Graduates are prepared for careers in clinics, schools, and other diverse settings.

  • Post-master's certificate program.
  • Online delivery format.
  • 18-32 credit hours.
  • Requires master's in nursing.
  • Prepares for national certification.
  • Focuses on holistic mental health care.
  • Includes psychopharmacology proficiency.
  • Covers psychiatric evaluation competency.
  • Two entry points for students.
  • GPA requirement of 3.00.

Graduate Certificate - Certificate of Graduate Study, Healthcare Leadership

Online Learning - Visit Website

USC's online Certificate of Graduate Study in Healthcare Leadership is a post-master's program designed for MSN-prepared nurses seeking leadership roles in health organizations. No GRE is required for admission; applicants need BSN and MSN from accredited institutions, a preferred 3.0 GPA, and an active RN license. The one-year curriculum, available full- or part-time, includes 224 precepted leadership hours and courses on financing healthcare, population analysis, health systems, and integrative processes. Fall and spring entry are offered, with costs varying and financial aid available. Graduates are eligible for certification exams and prepared for administrative and executive positions.

  • Online course format.
  • Completed within one year.
  • Full-time or part-time study.
  • Post-master's certificate program.
  • Healthcare Leadership concentration.
  • Prepares for leadership roles.
  • Requires BSN and MSN degrees.
  • Preferred GPA of 3.0.
  • Active RN license needed.
  • No GRE required.

Graduate Certificate - Certificate of Graduate Study, Nursing Informatics

Online Learning - Visit Website

USC's College of Nursing delivers an online Certificate of Graduate Study in Nursing Informatics for post-master's nurses. This 18-credit program spans three semesters and includes 224 clinical hours, emphasizing healthcare data management, clinical decision support, and patient outcome improvement. No GRE is required; applicants must have BSN and MSN degrees from accredited schools, a preferred 3.0 GPA, and an active RN license, along with three recommendations and a personal statement. Courses blend ITEC and NURS offerings. Fall and spring starts are available, and financial aid and scholarships are accessible. Graduates qualify for national certification exams.

  • 18 credit hours total.
  • Three semesters to complete.
  • Online course format.
  • Post-master's certificate program.
  • Includes 224 clinical hours.
  • Requires BSN and MSN degrees.
  • Preferred 3.0 GPA for admission.
  • Active RN license needed.
  • Three recommendation letters required.
  • Personal statement submission.

Graduate Certificate - Adult Gerontology-Acute Care Nurse Practitioner, Certificate

Online Learning - Visit Website

  • Post-master's certificate program.
  • Online delivery format.
  • Requires MSN degree.
  • 3.00 GPA minimum.
  • 30-32 credit hours.
  • Includes practicum courses.
  • Prepares for national certification.
  • Focus on acute care settings.
  • Adult and gerontology focus.
  • Advanced practice preparation.
Show 5 More Programs ˅
#2

Francis Marion University

Florence, SC - Public 4-Year - fmarion.edu

Graduate Certificate - Post-Master's Psychiatric Mental Health Nurse Practitioner Certificate

Online & Campus Based - Visit Website

Francis Marion University offers a Post-Master's Psychiatric Mental Health Nurse Practitioner Certificate in a hybrid format, blending online coursework with campus visits twice per semester. This 23-27 credit program includes 780 clinical practicum hours and prepares advanced practice nurses to provide mental health care across the lifespan, with an emphasis on rural populations. Designed for MSN-prepared nurses, it offers flexible full-time (four semesters) or part-time study. Students complete individualized gap analyses and arrange their own preceptors. Graduates are eligible for AANP and ANCC certification exams. The program requires an active unencumbered nursing license, criminal background check, drug screening, and malpractice insurance.

  • 23-27 credit hours.
  • 780 clinical practicum hours.
  • Hybrid program format.
  • Mostly online courses.
  • Campus visits twice per semester.
  • Full-time completion in four semesters.
  • Part-time study options available.
  • Requires MSN degree for admission.
  • Fall semester admission only.
  • Individualized gap analysis performed.
#3

Anderson University

Anderson, SC - Private 4-year - andersonuniversity.edu

Graduate Certificate - Psychiatric Mental Health Nurse Practitioner Certificate

Online & Campus Based - Visit Website

Anderson University offers a Psychiatric Mental Health Nurse Practitioner (PMHNP) Certificate for advanced practice nurses seeking specialized training. This hybrid, predominantly online program requires 22-24 credit hours and 750 clinical hours, with three campus days per semester in Greenville. Spanning 15 months with a January start, the curriculum prepares nurses for ANCC or AANP certification exams. Admission requires a master's or doctorate in Family Nurse Practitioner, along with completion of the Three P's. While 1-2 years of nursing experience is recommended, the program does not mention an entrance exam requirement. PMHNPs in South Carolina earn an average salary of $135,000, making this certificate a strong career investment.

  • 22-24 credit hours required.
  • Hybrid class format.
  • 15-month program duration.
  • January start date.
  • 750 clinical hours included.
  • Mostly online delivery.
  • Campus visits in Greenville.
  • Three campus days per semester.
  • Prepares for certification exams.
  • ANCC or AANP exam preparation.
#4

Medical University of South Carolina

Charleston, SC - Public 4-Year - musc.edu

Graduate Certificate - Psychiatric Mental Health Nurse Practitioner, Post-Graduate Certificate

Online Learning - Visit Website

Medical University of South Carolina offers an online Psychiatric Mental Health Nurse Practitioner Post-Graduate Certificate designed for certified APRNs seeking lifespan psychiatric-mental health certification. This 23-credit program is completed over four semesters, combining flexible online coursework with in-person clinical experiences. The curriculum emphasizes neuroscience, psychopharmacology, and advanced care management. No entrance examination, such as the GRE, is required for admission. In-state tuition is $835 per credit, with total estimated costs of $84,206; out-of-state tuition is $1,120 per credit, totaling approximately $91,046. Additional fees include a $50 application fee and a $485 matriculation fee. Federal financial aid is unavailable, but need-based scholarships may be available. Out-of-state students must obtain Board of Nursing approval for clinical placements.

  • 23 credits total
  • Four semester completion
  • Online learning mode
  • In-person clinical experiences
  • Designed for working professionals
  • For certified APRNs
  • Post-graduate certificate program
  • In-state tuition $835/credit
  • Out-of-state tuition $1,120/credit
  • Application fee $50
*Credit: National Center for Education Statistics, IPEDS 2025.

Post-Graduate Certificate in Nursing Admission Requirements in South Carolina

Regardless of which school you choose for your post-graduate nursing certificate, the admission requirements are going to be similar. Students should check the requirements for the school they plan to attend, but the requirements for admission to the post-graduate certificate programs at the University of South Carolina are a good example. The school requires:

  • A completed graduate school application
  • A bachelor's degree
  • Official transcripts from all previous schools
  • Official test scores
  • Letters of recommendation
  • An application fee
  • English proficiency requirements for non-citizens

See Related Articles

Post-Graduate Certificate in Nursing Classes and Courses

The courses required for each program vary depending on the specialty and the individual school's requirements. Most programs require some general nursing courses combined with courses that are directly related to the desired specialty. For example, the post-graduate nursing certificate for psychiatric mental health nurse practitioner from Anderson University Online requires the following courses:

  • Faith and Learning Overview
  • PMHNP I
  • Interprofessional Collaboration in Health Promotion
  • Advanced Assessment Processes in Mental Healthcare Across the Life Span
  • Management of Behavioral Health Populations Across the Life Span
  • Psychopharmacological Therapies Across the Life Span
  • Management of the Complex Mental Health Client Across the Life Span
  • PMHNP II
  • Certification Review Seminar – PMHNP

Program Length

Post-graduate nursing certificates can require anywhere from 9 to 30 credits. They usually take around two years to complete, but some may be completed more quickly. Some programs are designed to be taken part-time, which would take longer. However, graduate students may be able to participate in an accelerated program.

Tuition and Cost of Attendance

The cost of post-graduate education varies from school to school based on many factors. For example, public schools are almost always less expensive than private schools. In addition to tuition, students need to think about how much they will spending on housing, meals, books, supplies, and fees. The University of South Carolina provides a breakdown on how much students usually spend. USC students can expect to spend:

  • $12,688 for in-state tuition or $33,928 for out-of-state tuition
  • $8,218 for housing
  • $3,966 for meals
  • $1,085 for books and supplies

Online Post-Graduate Nursing Certificate Programs in South Carolina

At least four schools in South Carolina offer online post-graduate nursing programs. These programs are designed to fit into a working nurse's busy schedule so that students can continue to work while advancing their education. Online programs are usually flexible enough to accommodate even the busiest schedules, so they are great for adult students with families or other commitments.

Post-Graduate Certificate in Nursing Career Pathways in South Carolina

Most South Carolina post-graduate nursing certificates prepare the student to earn an Advanced Practice Registered Nurse designation in the area of specialty. Students must be licensed by the South Carolina Board of Nursing following completion of the program in order to earn the APRN designation. The programs available in South Carolina are:

Post-Graduate Nursing Certificate Salary & Job Outlook

The job outlook for Advanced Practice Registered Nurses is outstanding. The number of jobs is expected to grow 26% by 2028, which is much faster than the average growth rate. In 2018, nurse practitioners earned a median wage of $113,930 according to the Bureau of Labor Statistics. Some earned as much as $180,000 or more.

List of South Carolina Post-Graduate Certificate in Nursing Programs

If you're ready to take your APRN career to the next level, consider contacting one or more of these schools about their South Carolina post-graduate nursing programs.

Browse Our List of Programs

Browse our list of programs to find the right fit. Each entry shows the school's city and state, program highlights, and a link to its program page. Use the table to compare options side by side and learn what each school offers. We've made it easy to explore your choices. Start now and discover the program that matches your goals.
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Anderson, SC

Anderson University

  • Graduate Certificate - Psychiatric Mental Health Nurse Practitioner Certificate

    Online & Campus Based - Website

    • 22-24 credit hours required.
    • Hybrid class format.
    • 15-month program duration.
    • January start date.
    • 750 clinical hours included.
    • Mostly online delivery.
    • Campus visits in Greenville.
    • Three campus days per semester.

Charleston, SC

Medical University of South Carolina

  • Graduate Certificate - Psychiatric Mental Health Nurse Practitioner, Post-Graduate Certificate

    Online Learning - Website

    • 23 credits total
    • Four semester completion
    • Online learning mode
    • In-person clinical experiences
    • Designed for working professionals
    • For certified APRNs
    • Post-graduate certificate program
    • In-state tuition $835/credit

Columbia, SC

University of South Carolina

  • Graduate Certificate - Adult Gerontology-Acute Care Nurse Practitioner, Certificate

    Online Learning - Website

    • Post-master's certificate program.
    • Online delivery format.
    • Requires MSN degree.
    • 3.00 GPA minimum.
    • 30-32 credit hours.
    • Includes practicum courses.
    • Prepares for national certification.
    • Focus on acute care settings.
  • Graduate Certificate - Certificate of Graduate Study, Healthcare Leadership

    Online Learning - Website

    • Online course format.
    • Completed within one year.
    • Full-time or part-time study.
    • Post-master's certificate program.
    • Healthcare Leadership concentration.
    • Prepares for leadership roles.
    • Requires BSN and MSN degrees.
    • Preferred GPA of 3.0.
  • Graduate Certificate - Certificate of Graduate Study, Nursing Informatics

    Online Learning - Website

    • 18 credit hours total.
    • Three semesters to complete.
    • Online course format.
    • Post-master's certificate program.
    • Includes 224 clinical hours.
    • Requires BSN and MSN degrees.
    • Preferred 3.0 GPA for admission.
    • Active RN license needed.
  • Graduate Certificate - Family Nurse Practitioner, Certificate

    Online Learning - Website

    • Post-master's certificate program.
    • Requires master's degree in nursing.
    • Prepares for national certification.
    • 18-32 credit hours required.
    • Minimum 3.00 GPA needed.
    • Online program format.
    • Two entry points available.
    • Includes practicum courses.
  • Graduate Certificate - Nursing Education

    Online Learning - Website

    • National League of Nursing accredited
    • Apply by 2025-06-30
    • Full-time and part-time options
    • Starts fall
    • 3.0 GPA minimum
    • 3 letters of recommendation (minimum)
    • Prepares for CNE
    • Prepares for CNE certification exam
  • Graduate Certificate - Psychiatric Mental Health Nurse Practitioner, Certificate

    Online Learning - Website

    • Post-master's certificate program.
    • Online delivery format.
    • 18-32 credit hours.
    • Requires master's in nursing.
    • Prepares for national certification.
    • Focuses on holistic mental health care.
    • Includes psychopharmacology proficiency.
    • Covers psychiatric evaluation competency.

Florence, SC

Francis Marion University

  • Graduate Certificate - Post-Master's Psychiatric Mental Health Nurse Practitioner Certificate

    Online & Campus Based - Website

    • 23-27 credit hours.
    • 780 clinical practicum hours.
    • Hybrid program format.
    • Mostly online courses.
    • Campus visits twice per semester.
    • Full-time completion in four semesters.
    • Part-time study options available.
    • Requires MSN degree for admission.
*IPEDS 2025 statistics, sourced from NCES. https://nces.ed.gov/ipeds/